CD47 抗体
Quick Overview for CD47 抗体 (ABIN6796388)
抗原
See all CD47 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- Specific for human CD47, also known as integrin-associated protein, a 50kD glycoprotein expressed on all hematopoietic cell lines, epithelial cells, endothelial cells, fibroblasts and many tumor cell lines. CD47 is involved in several cellular processes including regulation of T cell and dendritic cell activation, regulation of neutrophil (PMN) chemotaxis, caspase-independent apoptosis, and may act as a signal transducer in the regulation of cation fluxes across cell membranes. CD47 has been identified as a ligand for the inhibitory macrophage receptor known as signal regulatory protein alpha (SIRPalpha) and as a receptor for thrombospondin-1. Cross-linking of CD47 with clone 1/1A4 co-stimulates the proliferation of T cells.
-
纯化方法
- Protein G purified
-
免疫原
-
Human erythrocytes.
Type of Immunogen: Cells -
亚型
- IgG2b
-
-
-
-
应用备注
- Approved: Flo (1:25 - 1:100), IHC, IHC-Fr, IP
-
说明
-
Target Species of Antibody: Human
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- PBS, 0.09 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- 4°C or -20°C, Avoid freeze-thaw cycles.
-
-
- CD47
-
别名
- CD47
-
背景
-
Name/Gene ID: CD47
Synonyms: CD47, CD47 antigen, CD47 Molecule, Integrin associated protein, Integrin-associated protein, Leukocyte surface antigen CD47, MER6, Protein MER6, Rh-related antigen, OA3, CD47 glycoprotein, IAP -
基因ID
- 961
抗原
-